| Cheap ibuprofen
medical use of the drug
ibuprofen
(Ibuprofenum)
General characteristics:
International and chemical name: ibuprofen, 1-2- (4-isobutylphenyl) -propionova acid;
basic physical and chemical properties: tablets, coated white with biconvex surface;
Composition: 1 tablet contains ibuprofen - 0.2 g;
auxiliary substances: potato starch, mahniyustearat or calcium stearate, polyvinyl ethyl cellulose of water-soluble, Tween -80, titanium dioxide, emulsion KE 10-16.
Cheap ibuprofen
Pharmacological group. Not steroidal anti-inflammatory and antirheumatic drugs. Derivatives of propionic acid. Ibuprofen. ATC code E 01 N 01a.
Farmakolohichni properties.
Pharmacodynamics.
Ibuprofen - nonsteroidal anti-inflammatory agent, a derivative of propionic acid. Has pronounced analgesic, antipyretic and anti-inflammatory properties. Effect of the drug based on inhibition syntezuprostahlandyniv. In addition, ibuprofen inhibits ADP and collagen-induced platelet aggregation.
The drug is more effective in the early stages of the inflammatory process without drastic changes in the joints. According to zapalnoyuaktyvnistyu inferior to indomethacin, current arena. However, keep in mind the inherent selectivity of individual drug effect, good tolerability, the absence of irritation of the gastrointestinal tract during prolonged, repeated use.
Cheap ibuprofen
Quickly and well absorbed in the gastrointestinal tract. When administered 0.2 g ibuprofen fasting internally, the maximum concentration in the blood is achieved within 30 - 45 minutes. The same dose pryynyataz food slowly absorbed and maximum concentration in the blood reaches 1.5 - 3 hours.
The effective concentration for therapeutic pain relief is 10 mg / l for against inflammatory - 15 mg / l. Binding to plasma proteins is 99%. Semi withdrawal period - 2 - 2,5hodyny, liver and kidneys increases to 3.5 hours. The drug is slowly penetrates the joint cavity, but is retained in the synovial tissue, forming a larger concentration than in plasma, and slowly excreted from it after discontinuation of the drug. Ibuprofen is actively metabolized in the liver to form inactive metabolites, which are eliminated in the urine in unchanged form.
Source: ibuprofen, instruction, use of the drug ibuprofen coated tablets, 0.2 grams of number 10, number 30, number 50, number 100
|