Buy * These items are located on site pharmacy network "Thetis" Pharmachologic effect: The drug restores normal response to sexual stimulation. Sam physiological mechanism that provides an erection is not possible without isolation of nitric oxide in the cavernous body during sexual stimulation. NO activates a special enzyme called guanylate cyclase, resulting in increased levels of cGMP (cyclic guanosine monophosphate), relax the muscles of the cavernous body and increased blood flow to the genitals. Sildenafil - the active ingredient of Viagra, is a selective inhibitor of PDE5 (phosphodiesterase type 5), which provides a breakdown of cGMP in the cavernous body. The preparation is characterized by peripheral action on the penile erection. It is noteworthy that sildenafil relaxing corpus cavernosum not directly, but uses the function of relaxing the nitrogen oxide. It is known that for a useful pharmacological action of the drug to sexual stimulation. The drug was well tolerated in healthy subjects after a single application of persons in an amount not to exceed 100 mg, did not cause clinically significant abnormalities. what is viagra super active Indications for use: The drug is prescribed for a variety of erectile dysfunction (usually psychogenic, organic or mixed). Mode of application: The tablets of the drug is taken orally, about one hour before planned sexual intercourse. The optimal single dose for adults is 50 mg once a day. Considering the individual tolerance and efficacy, the dose may be reduced to 25 mg or increased to 100 mg. 100 mg per day - this is the maximum single dose. it is not necessary to change the standard dosage for the elderly. what is viagra super active Side effects: The drug is well tolerated. In some cases, side effects were seen: - Central nervous system (insomnia, dizziness and increased muscle tone); - Cardiovascular (flushing, headache, vasodilatation); - Musculoskeletal system (pain in the joints and muscles); - Of the gastrointestinal tract (nausea, diarrhea, dyspepsia); - Skin (rash); - Senses (conjunctivitis, blurred vision, increased svetovospriyatie, a change of color); - Of the respiratory system (breathing disorders, pharyngitis, sinusitis, rhinitis, nasal congestion, respiratory tract infection); - Urogenital system (work prostate disorder, urinary infections channels). Among other side effects were observed symptoms of influenza, back pain or stomach. Rare cases of priapism have been observed. Contraindications: The drug is contraindicated in persons with hypersensitivity to the drug and with anatomical deformation of the penis (Peyronie's disease, cavernous fibrosis, angulation). Also, do not use this drug for the following offenses: - An increased tendency to bleeding; - Exacerbation of peptic ulcer disease of the gastrointestinal tract; - Violations of the liver, especially severe renal failure or cirrhosis; - Diseases that develop priapism, including leukemia, multiple myeloma and sickle cell anemia; - Severe hypotension or hypertension; Various heart disease, including unstable angina, arrhythmia dangerous form and heart failure. If the patient has had a stroke or myocardial infarction, in the next six months, the drug should not be used. Also, Viagra is not indicated for children. It is strictly forbidden the simultaneous use of the drug with nitrates and nitric oxide donators. Men who are contraindicated for sexual activity, Viagra should not be used. Pregnancy: This drug is not indicated for women. Reproductive experiments were conducted in rabbits and rats, and the results have not revealed teratogenic effects of Viagra. The fetus develops without deviations and violations. Also investigated the morphology and activity of sperm from volunteers in single dose. No irregularities were found. Interaction with other drugs: Admission erythromycin, cimetidine and ketoconazole is characterized by a decrease in clearance and subsequent increase in the content of Sildenafil in the patient's blood plasma. Viagra in conjunction with sodium nitroprusside enhances its antiplatelet effect. Also, when combined with nitrate medication enhances their antihypertensive effect. It can even lead to death. It is also dangerous for the life of the drug simultaneously with oral hypoglycemic drugs, BCCI, and beta-blockers. Overdose: Studies have shown that when patients overdose Vahram more clearly apparent side effects. In this case, the treatment must be used symptomatically. Dialysis is not effective because the active substance is actively and rapidly bound to plasma proteins. Product form: Viagra is distributed as a film-coated tablets. The tablets are in a blister pack made of aluminum foil, which in turn is in a carton box. Storage conditions: Viagra store in a dry place inaccessible to children. Storage temperature should not exceed 30 ° C. Shelf life is 2 years. Do not use expired medication. Synonyms: Sildenafil (Sildenafil) See also the list of analogues of the drug Viagra. what is viagra super active Composition: The main active ingredient - sildenafil, presented in the form of citrate. As auxiliary substances are used: anhydrous calcium hydrogen phosphate, magnesium stearate, croscarmellose sodium and titanium dioxide (E 171), triacetin, MCC, hypromellose, indigo carmine Aluminium lacquer (E 132), lactose. Pharmacological group: Means, used for the treatment of sexual dysfunction in men Active substance: Sildenafil Additionally: The drug released from pharmacies by prescription. Attention! Description "Viagra" drug on this page is a simplified and enlarged version of the official instructions for use. Before purchasing or using the product, you should consult your doctor and see the summary approved by the manufacturer. preparation of information being provided is for informational purposes and should not be used as a guide to self-healing. Only a doctor can decide on the appointment of the drug, and to determine the doses and methods of application.